Polynucleotides
What do Polynucleotides do?
Polynucleotide treatment is a skin-rejuvenating therapy that involves injecting polynucleotides (natural DNA fragments) into the skin to promote healing, hydration, and regeneration. It’s often used in aesthetic medicine for anti-aging, scar treatment, and improving skin quality.
How it works:
Polynucleotides attract water and stimulate fibroblasts (cells that produce collagen and elastin).
This enhances skin elasticity, firmness, and texture.
They also reduce inflammation and promote tissue repair.
Common areas treated:
Face (especially under-eye area)
Neck
Décolletage
Hands
Scalp (for hair restoration)
Expected results:
Improved skin hydration and glow
Smoother, firmer, more elastic skin
Reduced fine lines and wrinkles
Better skin tone and texture
Mild scar and pigmentation improvement
Gradual, natural-looking effects
When to expect results:
Visible results typically start after 2–3 sessions, spaced a few weeks apart.
Full results usually appear in 6–8 weeks.
Is it safe?
Generally very safe, as polynucleotides are biocompatible and well-tolerated.
Mild swelling, redness, or bruising may occur post-treatment.
Who can and can’t receive them
Polynucleotide injections are relatively safe. However they should be avoided if you are/have:
- Pregnant
- Breastfeeding
- Under 18 years old
- Kidney disease
- Liver disease
- Allergies - raise these prior to treatment
Consultation
In our consultation, we’ll discuss the benefits of Polynucleotide injections.
They are suitable treatment for eyes and the full face.
For the eyes and the face, it’s recommended that Polynucleotide injections are given three times, two to three weeks apart. For maintenance, subsequent injections can be received once, six to nine months thereafter.
Depending on the area, either a cannula or a needle may be used to administer the injection.
After treatment/Follow-Up
After treatment, the patient can expect mild swelling or raised bumps that will go down 48 hours.
What are the benefits of polynucleotides on the face?
Polynucleotide injections are anti-aging, and help with inflammation, dark circles, and skin hydration.
They help to rejuvenate the skin from within.
How long do polynucleotide injections last?
Polynucleotide treatment lasts for 6-9 months, after which a maintenance treatment can be scheduled.